A27S (p.Ala27Ser) variant of IL6R (P08887)
A27S (p.Ala27Ser) in IL6R (P08887) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.09 / 1. The record also includes population frequency data, published literature, and structural context.
A27S (p.Ala27Ser) variant details
- p.Ala27Ser
- gnomAD 1-154405708-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.0924
- REVEL 0.01
- MetaLR 0.01
- MetaSVM -0.94
- CADD 4.31
- PolyPhen-2 0.03
- SIFT 0.38
- Population evidence available
- Structural context available
- Literature evidence available