A27G (p.Ala27Gly) variant of IL6R (P08887)
A27G (p.Ala27Gly) in IL6R (P08887) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data, published literature, and structural context.
A27G (p.Ala27Gly) variant details
- p.Ala27Gly
- gnomAD 1-154405709-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.104
- REVEL 0.01
- MetaLR 0.01
- MetaSVM -0.97
- CADD 8.78
- PolyPhen-2 0.04
- SIFT 0.18
- Population evidence available
- Structural context available
- Literature evidence available