A27E (p.Ala27Glu) variant of IL6R (P08887)
A27E (p.Ala27Glu) in IL6R (P08887) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data, published literature, and structural context.
A27E (p.Ala27Glu) variant details
- p.Ala27Glu
- gnomAD 1-154405709-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.105
- REVEL 0.03
- MetaLR 0.01
- MetaSVM -0.98
- CADD 5.17
- PolyPhen-2 0.19
- SIFT 0.40
- Population evidence available
- Structural context available
- Literature evidence available