A21V (p.Ala21Val) variant of IL6R (P08887)
A21V (p.Ala21Val) in IL6R (P08887) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.07 / 1. The record also includes population frequency data, published literature, and structural context.
A21V (p.Ala21Val) variant details
- p.Ala21Val
- gnomAD 1-154405691-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.0723
- REVEL 0.02
- MetaLR 0.01
- MetaSVM -0.90
- CADD 0.87
- PolyPhen-2 0.00
- SIFT 1.00
- Population evidence available
- Structural context available
- Literature evidence available