A21T (p.Ala21Thr) variant of IL6R (P08887)
A21T (p.Ala21Thr) in IL6R (P08887) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data, published literature, and structural context.
A21T (p.Ala21Thr) variant details
- p.Ala21Thr
- gnomAD 1-154405690-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.223
- REVEL 0.01
- MetaLR 0.02
- MetaSVM -0.95
- CADD 10.30
- PolyPhen-2 0.01
- SIFT 0.36
- Population evidence available
- Structural context available
- Literature evidence available