A21P (p.Ala21Pro) variant of IL6R (P08887)
A21P (p.Ala21Pro) in IL6R (P08887) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
A21P (p.Ala21Pro) variant details
- p.Ala21Pro
- Ensembl rs1558292924
- Missense
- Variant Prioritization Score for Impact Estimate 0.302
- REVEL 0.07
- CADD 18.50
- PolyPhen-2 0.91
- SIFT 0.17
- Most common in the Latino/Admixed American population (allele frequency 2.9e-05)
- Structural context available