A19V (p.Ala19Val) variant of IL6R (P08887)
A19V (p.Ala19Val) in IL6R (P08887) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
A19V (p.Ala19Val) variant details
- p.Ala19Val
- Ensembl rs1687663717
- Missense
- Variant Prioritization Score for Impact Estimate 0.215
- REVEL 0.04
- CADD 18.30
- PolyPhen-2 0.57
- SIFT 0.11
- Most common in the Latino/Admixed American population (allele frequency 6.5e-05)
- Structural context available