A19E (p.Ala19Glu) variant of IL6R (P08887)
A19E (p.Ala19Glu) in IL6R (P08887) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data, published literature, and structural context.
A19E (p.Ala19Glu) variant details
- p.Ala19Glu
- gnomAD 1-154405685-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.19
- REVEL 0.04
- MetaLR 0.02
- MetaSVM -1.01
- CADD 12.80
- PolyPhen-2 0.08
- SIFT 0.23
- Population evidence available
- Structural context available
- Literature evidence available