A18T (p.Ala18Thr) variant of IL6R (P08887)
A18T (p.Ala18Thr) in IL6R (P08887) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data, published literature, and structural context.
A18T (p.Ala18Thr) variant details
- p.Ala18Thr
- gnomAD 1-154405681-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.117
- REVEL 0.02
- MetaLR 0.01
- MetaSVM -0.99
- CADD 6.63
- PolyPhen-2 0.00
- SIFT 0.51
- Population evidence available
- Structural context available
- Literature evidence available