A15S (p.Ala15Ser) variant of IL6R (P08887)
A15S (p.Ala15Ser) in IL6R (P08887) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data, published literature, and structural context.
A15S (p.Ala15Ser) variant details
- p.Ala15Ser
- gnomAD 1-154405672-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.114
- REVEL 0.03
- MetaLR 0.01
- MetaSVM -0.99
- CADD 6.44
- PolyPhen-2 0.10
- SIFT 0.09
- Population evidence available
- Structural context available
- Literature evidence available