A15E (p.Ala15Glu) variant of IL6R (P08887)
A15E (p.Ala15Glu) in IL6R (P08887) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data, published literature, and structural context.
A15E (p.Ala15Glu) variant details
- p.Ala15Glu
- gnomAD 1-154405673-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.159
- REVEL 0.06
- MetaLR 0.03
- MetaSVM -1.07
- CADD 11.30
- PolyPhen-2 0.33
- SIFT 0.08
- Population evidence available
- Structural context available
- Literature evidence available