A14T (p.Ala14Thr) variant of IL6R (P08887)
A14T (p.Ala14Thr) in IL6R (P08887) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data, published literature, and structural context.
A14T (p.Ala14Thr) variant details
- p.Ala14Thr
- gnomAD 1-154405669-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.173
- REVEL 0.05
- MetaLR 0.02
- MetaSVM -0.99
- CADD 15.30
- PolyPhen-2 0.02
- SIFT 0.26
- Population evidence available
- Structural context available
- Literature evidence available