A14S (p.Ala14Ser) variant of IL6R (P08887)
A14S (p.Ala14Ser) in IL6R (P08887) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data, published literature, and structural context.
A14S (p.Ala14Ser) variant details
- p.Ala14Ser
- gnomAD 1-154405669-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.167
- REVEL 0.04
- MetaLR 0.02
- MetaSVM -0.98
- CADD 13.40
- PolyPhen-2 0.02
- SIFT 0.29
- Population evidence available
- Structural context available
- Literature evidence available