A11V (p.Ala11Val) variant of IL6R (P08887)
A11V (p.Ala11Val) in IL6R (P08887) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
A11V (p.Ala11Val) variant details
- p.Ala11Val
- gnomAD rs1273991580
- Missense
- Variant Prioritization Score for Impact Estimate 0.161
- REVEL 0.05
- CADD 16.10
- PolyPhen-2 0.67
- SIFT 0.55
- Most common in the Non-Finnish European population (allele frequency 9.3e-07)
- Structural context available