A11T (p.Ala11Thr) variant of IL6R (P08887)
A11T (p.Ala11Thr) in IL6R (P08887) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
A11T (p.Ala11Thr) variant details
- p.Ala11Thr
- TOPMed rs1240042661
- gnomAD rs1240042661
- Missense
- Variant Prioritization Score for Impact Estimate 0.184
- REVEL 0.09
- CADD 14.40
- PolyPhen-2 0.39
- SIFT 0.27
- Population evidence available
- Structural context available