A11S (p.Ala11Ser) variant of IL6R (P08887)
A11S (p.Ala11Ser) in IL6R (P08887) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data and structural context.
A11S (p.Ala11Ser) variant details
- p.Ala11Ser
- TOPMed rs1240042661
- gnomAD rs1240042661
- Missense
- Variant Prioritization Score for Impact Estimate 0.146
- REVEL 0.05
- CADD 11.30
- PolyPhen-2 0.10
- SIFT 0.32
- Most common in the Non-Finnish European population (allele frequency 9.3e-07)
- Structural context available