A11D (p.Ala11Asp) variant of IL6R (P08887)
A11D (p.Ala11Asp) in IL6R (P08887) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data, published literature, and structural context.
A11D (p.Ala11Asp) variant details
- p.Ala11Asp
- gnomAD 1-154405661-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.216
- REVEL 0.14
- MetaLR 0.06
- MetaSVM -1.11
- CADD 18.00
- PolyPhen-2 0.69
- SIFT 0.08
- Population evidence available
- Structural context available
- Literature evidence available