A10V (p.Ala10Val) variant of IL6R (P08887)
A10V (p.Ala10Val) in IL6R (P08887) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data, published literature, and structural context.
A10V (p.Ala10Val) variant details
- p.Ala10Val
- gnomAD 1-154405658-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.138
- REVEL 0.04
- MetaLR 0.01
- MetaSVM -0.93
- CADD 12.30
- PolyPhen-2 0.01
- SIFT 1.00
- Population evidence available
- Structural context available
- Literature evidence available