A10T (p.Ala10Thr) variant of IL6R (P08887)
A10T (p.Ala10Thr) in IL6R (P08887) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data, published literature, and structural context.
A10T (p.Ala10Thr) variant details
- p.Ala10Thr
- gnomAD 1-154405657-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.13
- REVEL 0.07
- MetaLR 0.00
- MetaSVM -0.92
- CADD 13.80
- PolyPhen-2 0.00
- SIFT 0.94
- Population evidence available
- Structural context available
- Literature evidence available