A10S (p.Ala10Ser) variant of IL6R (P08887)
A10S (p.Ala10Ser) in IL6R (P08887) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data, published literature, and structural context.
A10S (p.Ala10Ser) variant details
- p.Ala10Ser
- gnomAD 1-154405657-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.12
- REVEL 0.07
- MetaLR 0.01
- MetaSVM -0.97
- CADD 12.40
- PolyPhen-2 0.04
- SIFT 0.46
- Population evidence available
- Structural context available
- Literature evidence available