A10P (p.Ala10Pro) variant of IL6R (P08887)
A10P (p.Ala10Pro) in IL6R (P08887) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data, published literature, and structural context.
A10P (p.Ala10Pro) variant details
- p.Ala10Pro
- gnomAD 1-154405657-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.155
- REVEL 0.12
- MetaLR 0.01
- MetaSVM -0.95
- CADD 16.60
- PolyPhen-2 0.00
- SIFT 0.24
- Population evidence available
- Structural context available
- Literature evidence available