A10G (p.Ala10Gly) variant of IL6R (P08887)
A10G (p.Ala10Gly) in IL6R (P08887) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data, published literature, and structural context.
A10G (p.Ala10Gly) variant details
- p.Ala10Gly
- gnomAD 1-154405658-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.143
- REVEL 0.05
- MetaLR 0.01
- MetaSVM -0.94
- CADD 14.80
- PolyPhen-2 0.00
- SIFT 0.23
- Population evidence available
- Structural context available
- Literature evidence available