A10D (p.Ala10Asp) variant of IL6R (P08887)
A10D (p.Ala10Asp) in IL6R (P08887) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data, published literature, and structural context.
A10D (p.Ala10Asp) variant details
- p.Ala10Asp
- gnomAD 1-154405658-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.164
- REVEL 0.10
- MetaLR 0.02
- MetaSVM -1.01
- CADD 13.00
- PolyPhen-2 0.16
- SIFT 0.26
- Population evidence available
- Structural context available
- Literature evidence available