Y59F (p.Tyr59Phe) variant of IL6 (Interleukin-6)
Y59F (p.Tyr59Phe) in IL6 (Interleukin-6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data, published literature, and structural context.
Y59F (p.Tyr59Phe) variant details
- p.Tyr59Phe
- gnomAD 7-22727600-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.158
- REVEL 0.12
- CADD 2.16
- PolyPhen-2 0.01
- SIFT 0.45
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available
- Literature evidence available