V39A (p.Val39Ala) variant of IL6 (Interleukin-6)
V39A (p.Val39Ala) in IL6 (Interleukin-6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data and structural context.
V39A (p.Val39Ala) variant details
- p.Val39Ala
- gnomAD rs769904935
- Missense
- Variant Prioritization Score for Impact Estimate 0.198
- REVEL 0.25
- MetaLR 0.14
- MetaSVM -0.95
- CADD 4.93
- PolyPhen-2 0.04
- SIFT 0.36
- Most common in the East Asian population (allele frequency 5e-05)
- Structural context available