T6A (p.Thr6Ala) variant of IL6 (Interleukin-6)
T6A (p.Thr6Ala) in IL6 (Interleukin-6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data and structural context.
T6A (p.Thr6Ala) variant details
- p.Thr6Ala
- 1000Genomes rs569143621
- TOPMed rs569143621
- gnomAD rs569143621
- Missense
- Variant Prioritization Score for Impact Estimate 0.4
- REVEL 0.15
- MetaLR 0.42
- MetaSVM -0.60
- CADD 17.40
- PolyPhen-2 0.11
- SIFT 0.29
- Most common in the 1KG:KHV population (allele frequency 0.005)
- Structural context available