S7T (p.Ser7Thr) variant of IL6 (Interleukin-6)
S7T (p.Ser7Thr) in IL6 (Interleukin-6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data and structural context.
S7T (p.Ser7Thr) variant details
- p.Ser7Thr
- gnomAD rs1415468375
- Missense
- Variant Prioritization Score for Impact Estimate 0.374
- REVEL 0.30
- MetaLR 0.44
- MetaSVM -0.67
- CADD 23.30
- PolyPhen-2 0.31
- SIFT 0.21
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available