S7G (p.Ser7Gly) variant of IL6 (Interleukin-6)
S7G (p.Ser7Gly) in IL6 (Interleukin-6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
S7G (p.Ser7Gly) variant details
- p.Ser7Gly
- gnomAD rs1212373109
- Missense
- Variant Prioritization Score for Impact Estimate 0.337
- REVEL 0.27
- MetaLR 0.58
- MetaSVM -0.57
- CADD 22.60
- PolyPhen-2 0.17
- SIFT 1.00
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available