R44T (p.Arg44Thr) variant of IL6 (Interleukin-6)
R44T (p.Arg44Thr) in IL6 (Interleukin-6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
R44T (p.Arg44Thr) variant details
- p.Arg44Thr
- Ensembl rs2128174113
- Missense
- Variant Prioritization Score for Impact Estimate 0.275
- REVEL 0.21
- MetaLR 0.40
- MetaSVM -0.55
- CADD 6.93
- PolyPhen-2 0.25
- SIFT 0.11
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available