P42L (p.Pro42Leu) variant of IL6 (Interleukin-6)
P42L (p.Pro42Leu) in IL6 (Interleukin-6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data, published literature, and structural context.
P42L (p.Pro42Leu) variant details
- p.Pro42Leu
- gnomAD 7-22727549-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.2
- REVEL 0.12
- CADD 21.10
- PolyPhen-2 0.72
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available