P31R (p.Pro31Arg) variant of IL6 (Interleukin-6)
P31R (p.Pro31Arg) in IL6 (Interleukin-6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
P31R (p.Pro31Arg) variant details
- p.Pro31Arg
- ExAC rs778465778
- TOPMed rs778465778
- gnomAD rs778465778
- Missense
- Variant Prioritization Score for Impact Estimate 0.159
- REVEL 0.17
- MetaLR 0.34
- MetaSVM -0.72
- CADD 0.31
- PolyPhen-2 0.01
- SIFT 0.39
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available