P23S (p.Pro23Ser) variant of IL6 (Interleukin-6)
P23S (p.Pro23Ser) in IL6 (Interleukin-6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data and structural context.
P23S (p.Pro23Ser) variant details
- p.Pro23Ser
- TOPMed rs1335707674
- Missense
- Variant Prioritization Score for Impact Estimate 0.196
- REVEL 0.09
- MetaLR 0.17
- MetaSVM -0.94
- CADD 18.00
- PolyPhen-2 0.02
- SIFT 0.02
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available