N2I (p.Asn2Ile) variant of IL6 (Interleukin-6)
N2I (p.Asn2Ile) in IL6 (Interleukin-6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
N2I (p.Asn2Ile) variant details
- p.Asn2Ile
- 1000Genomes rs200700194
- ExAC rs200700194
- gnomAD rs200700194
- Missense
- Variant Prioritization Score for Impact Estimate 0.274
- REVEL 0.22
- MetaLR 0.41
- MetaSVM -0.61
- CADD 22.90
- PolyPhen-2 0.34
- SIFT 0.05
- Most common in the 1KG:JPT population (allele frequency 0.0049)
- Structural context available