L47I (p.Leu47Ile) variant of IL6 (Interleukin-6)
L47I (p.Leu47Ile) in IL6 (Interleukin-6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data, published literature, and structural context.
L47I (p.Leu47Ile) variant details
- p.Leu47Ile
- gnomAD 7-22727563-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.174
- REVEL 0.22
- CADD 6.37
- PolyPhen-2 0.20
- SIFT 0.20
- Population evidence available
- Structural context available
- Literature evidence available