L47F (p.Leu47Phe) variant of IL6 (Interleukin-6)
L47F (p.Leu47Phe) in IL6 (Interleukin-6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data, published literature, and structural context.
L47F (p.Leu47Phe) variant details
- p.Leu47Phe
- gnomAD 7-22727563-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.194
- REVEL 0.26
- CADD 6.49
- PolyPhen-2 0.02
- SIFT 0.45
- Population evidence available
- Structural context available
- Literature evidence available