L22L (p.Leu22Leu) variant of IL6 (Interleukin-6)
L22L (p.Leu22Leu) in IL6 (Interleukin-6) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data, published literature, and structural context.
L22L (p.Leu22Leu) variant details
- p.Leu22Leu
- rs1207045699
- gnomAD 7-22727490-G-A
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.309
- CADD 10.80
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available
- Literature evidence available