L16V (p.Leu16Val) variant of IL6 (Interleukin-6)
L16V (p.Leu16Val) in IL6 (Interleukin-6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data, published literature, and structural context.
L16V (p.Leu16Val) variant details
- p.Leu16Val
- gnomAD 7-22727470-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.343
- REVEL 0.33
- MetaLR 0.51
- MetaSVM -0.07
- CADD 23.80
- PolyPhen-2 0.99
- SIFT 0.03
- Population evidence available
- Structural context available
- Literature evidence available