L16M (p.Leu16Met) variant of IL6 (Interleukin-6)
L16M (p.Leu16Met) in IL6 (Interleukin-6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data, published literature, and structural context.
L16M (p.Leu16Met) variant details
- p.Leu16Met
- gnomAD 7-22727470-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.364
- REVEL 0.35
- MetaLR 0.56
- MetaSVM 0.04
- CADD 24.20
- PolyPhen-2 1.00
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available