K55R (p.Lys55Arg) variant of IL6 (Interleukin-6)
K55R (p.Lys55Arg) in IL6 (Interleukin-6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.09 / 1. The record also includes population frequency data and structural context.
K55R (p.Lys55Arg) variant details
- p.Lys55Arg
- 1000Genomes rs541074925
- ExAC rs541074925
- TOPMed rs541074925
- gnomAD rs541074925
- Missense
- Variant Prioritization Score for Impact Estimate 0.0922
- REVEL 0.02
- MetaLR 0.03
- MetaSVM -1.05
- CADD 4.80
- PolyPhen-2 0.04
- SIFT 0.37
- Most common in the 1KG:STU population (allele frequency 0.0051)
- Structural context available