K37R (p.Lys37Arg) variant of IL6 (Interleukin-6)
K37R (p.Lys37Arg) in IL6 (Interleukin-6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data, published literature, and structural context.
K37R (p.Lys37Arg) variant details
- p.Lys37Arg
- gnomAD 7-22727534-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.194
- REVEL 0.12
- CADD 17.20
- PolyPhen-2 0.76
- SIFT 0.08
- Most common in the East Asian population (allele frequency 5e-05)
- Structural context available
- Literature evidence available