I60F (p.Ile60Phe) variant of IL6 (Interleukin-6)
I60F (p.Ile60Phe) in IL6 (Interleukin-6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data and structural context.
I60F (p.Ile60Phe) variant details
- p.Ile60Phe
- TOPMed rs1275239114
- gnomAD rs1275239114
- Missense
- Variant Prioritization Score for Impact Estimate 0.397
- REVEL 0.30
- MetaLR 0.12
- MetaSVM -1.02
- CADD 22.30
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available