G33V (p.Gly33Val) variant of IL6 (Interleukin-6)
G33V (p.Gly33Val) in IL6 (Interleukin-6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
G33V (p.Gly33Val) variant details
- p.Gly33Val
- gnomAD rs1362940639
- Missense
- Variant Prioritization Score for Impact Estimate 0.228
- REVEL 0.20
- MetaLR 0.39
- MetaSVM -0.62
- CADD 16.20
- PolyPhen-2 0.70
- SIFT 0.07
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available