G33A (p.Gly33Ala) variant of IL6 (Interleukin-6)
G33A (p.Gly33Ala) in IL6 (Interleukin-6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
G33A (p.Gly33Ala) variant details
- p.Gly33Ala
- gnomAD rs1362940639
- Missense
- Variant Prioritization Score for Impact Estimate 0.139
- REVEL 0.12
- MetaLR 0.22
- MetaSVM -0.86
- CADD 4.74
- PolyPhen-2 0.08
- SIFT 0.41
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available