G17V (p.Gly17Val) variant of IL6 (Interleukin-6)
G17V (p.Gly17Val) in IL6 (Interleukin-6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.53 / 1. The record also includes population frequency data and structural context.
G17V (p.Gly17Val) variant details
- p.Gly17Val
- TOPMed rs1282201857
- Missense
- Variant Prioritization Score for Impact Estimate 0.527
- REVEL 0.54
- MetaLR 0.50
- MetaSVM -0.04
- CADD 25.80
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available