G17R (p.Gly17Arg) variant of IL6 (Interleukin-6)
G17R (p.Gly17Arg) in IL6 (Interleukin-6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.62 / 1. The record also includes population frequency data and structural context.
G17R (p.Gly17Arg) variant details
- p.Gly17Arg
- Ensembl rs2128174068
- Missense
- Variant Prioritization Score for Impact Estimate 0.617
- REVEL 0.54
- MetaLR 0.51
- MetaSVM 0.02
- CADD 28.40
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available