G10R (p.Gly10Arg) variant of IL6 (Interleukin-6)
G10R (p.Gly10Arg) in IL6 (Interleukin-6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
G10R (p.Gly10Arg) variant details
- p.Gly10Arg
- Ensembl rs937615940
- Missense
- Variant Prioritization Score for Impact Estimate 0.281
- REVEL 0.34
- AlphaMissense 0.12
- MetaLR 0.11
- MetaSVM -0.92
- CADD 12.60
- PolyPhen-2 0.00
- Most common in the Ashkenazi Jewish population (allele frequency 3.8e-05)
- Structural context available