G10A (p.Gly10Ala) variant of IL6 (Interleukin-6)
G10A (p.Gly10Ala) in IL6 (Interleukin-6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
G10A (p.Gly10Ala) variant details
- p.Gly10Ala
- ExAC rs762283178
- gnomAD rs762283178
- Missense
- Variant Prioritization Score for Impact Estimate 0.212
- REVEL 0.17
- MetaLR 0.20
- MetaSVM -0.97
- CADD 11.70
- PolyPhen-2 0.01
- SIFT 0.75
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available