F9S (p.Phe9Ser) variant of IL6 (Interleukin-6)
F9S (p.Phe9Ser) in IL6 (Interleukin-6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data and structural context.
F9S (p.Phe9Ser) variant details
- p.Phe9Ser
- gnomAD rs1383764310
- Missense
- Variant Prioritization Score for Impact Estimate 0.365
- REVEL 0.33
- MetaLR 0.47
- MetaSVM -0.21
- CADD 24.20
- PolyPhen-2 0.06
- SIFT 0.00
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available