F26L (p.Phe26Leu) variant of IL6 (Interleukin-6)
F26L (p.Phe26Leu) in IL6 (Interleukin-6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
F26L (p.Phe26Leu) variant details
- p.Phe26Leu
- gnomAD rs1784032100
- Missense
- Variant Prioritization Score for Impact Estimate 0.215
- REVEL 0.11
- MetaLR 0.22
- MetaSVM -0.77
- CADD 8.90
- PolyPhen-2 0.02
- SIFT 0.18
- Most common in the South Asian population (allele frequency 0.00041)
- Structural context available