F14L (p.Phe14Leu) variant of IL6 (Interleukin-6)
F14L (p.Phe14Leu) in IL6 (Interleukin-6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data and structural context.
F14L (p.Phe14Leu) variant details
- p.Phe14Leu
- ExAC rs760962452
- gnomAD rs760962452
- Missense
- Variant Prioritization Score for Impact Estimate 0.43
- REVEL 0.27
- MetaLR 0.37
- MetaSVM -0.36
- CADD 21.90
- PolyPhen-2 0.44
- SIFT 0.10
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available